Title : TLR (Toll-Like Receptor) 4 Antagonism Prevents Left Ventricular Hypertrophy and Dysfunction Caused by Neonatal Hyperoxia Exposure in Rats.

Pub. Date : 2019 Oct

PMID : 31476902






3 Functional Relationships(s)
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1 The current study sought to investigate the role of TLR4 signaling in neonatal oxygen-induced cardiomyopathy. Oxygen toll-like receptor 4 Rattus norvegicus
2 At day 10, cardiac TLR4, Il (interleukin) 18, and Il1beta expression were increased in oxygen-exposed compared with room air controls. Oxygen toll-like receptor 4 Rattus norvegicus
3 This study indicates that neonatal exposure to high oxygen programs TLR4 activation, which contributes to cardiac remodeling and dysfunction. Oxygen toll-like receptor 4 Rattus norvegicus