Title : High Amplification of the Antiviral Activity of Curcumin through Transformation into Carbon Quantum Dots.

Pub. Date : 2019 Oct

PMID : 31468672






3 Functional Relationships(s)
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1 The results reveal that curcumin possesses insignificant inhibitory activity against EV71 infection in RD cells [half-maximal effective concentration (EC50 ) >200 microg mL-1 ] but exhibits high cytotoxicity toward RD cells (half-maximal cytotoxic concentration (CC50 ) <13 microg mL-1 ). Curcumin L1 cell adhesion molecule Mus musculus
2 The results reveal that curcumin possesses insignificant inhibitory activity against EV71 infection in RD cells [half-maximal effective concentration (EC50 ) >200 microg mL-1 ] but exhibits high cytotoxicity toward RD cells (half-maximal cytotoxic concentration (CC50 ) <13 microg mL-1 ). Curcumin L1 cell adhesion molecule Mus musculus
3 The EC50 (0.2 microg mL-1 ) and CC50 (452.2 microg mL-1 ) of Cur-CQDs are >1000-fold lower and >34-fold higher, respectively, than those of curcumin, demonstrating their far superior antiviral capabilities and high biocompatibility. Curcumin L1 cell adhesion molecule Mus musculus