Pub. Date : 2019
PMID : 31467666
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin represses the pathophysiology of AAA by suppressing the activation of PI3K/AKT/mTOR/autophagy pathway in ApoE-/- mice. | Metformin | thymoma viral proto-oncogene 1 | Mus musculus |
| 2 | In addition, metformin significantly suppressed the activation of the PI3K/AKT/mToR pathway and decreased the mRNA and protein levels of LC3B and Beclin1, which were induced by Ang-II. | Metformin | thymoma viral proto-oncogene 1 | Mus musculus |
| 3 | Conclusions: Metformin represses the pathophysiology of AAA by inhibiting the activation of PI3K/AKT/mTOR/autophagy pathway. | Metformin | thymoma viral proto-oncogene 1 | Mus musculus |