Title : A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and -F on Immune Cells.

Pub. Date : 2019 Sep 11

PMID : 31460762






1 Functional Relationships(s)
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1 Here, we report the development of a ligand of Siglec-8 and its closest murine functional orthologue Siglec-F that is capable of targeting liposomes to cells expressing Siglec-8 or -F. A glycan microarray library of synthetic 9-N-sulfonyl sialoside analogues was screened to identify potential lead compounds. 9-n-sulfonyl sialoside sialic acid binding Ig-like lectin F Mus musculus