Title : Affinity labeling the DNA polymerase alpha complex. Identification of subunits containing the DNA polymerase active site and an important regulatory nucleotide-binding site.

Pub. Date : 1988 Dec 15

PMID : 3143725






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Pyridoxal 5"-phosphate (PLP) inhibits DNA polymerase activity of the intact multifunctional DNA polymerase alpha complex by binding at either of two sites which can be distinguished on the basis of differential substrate protection. Pyridoxal Phosphate DNA polymerase alpha 1, catalytic subunit Homo sapiens