Pub. Date : 2019 Aug
PMID : 31418371
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The expression of P53 mRNA increased in KMS-18 cells after treatment of decitabine (P<0.05). | Decitabine | tumor protein p53 | Homo sapiens |
| 2 | The methylation status of the P53 gene promoter in KMS-18 cells could be partially reversed by decitabine. | Decitabine | tumor protein p53 | Homo sapiens |
| 3 | CONCLUSION: Decitabine can inhibit the proliferation of KMS-18 cells and induce their apoptosis, its mechanism ralates with partially reversing the methylation of P53 gene promoter in KMS-18 cells. | Decitabine | tumor protein p53 | Homo sapiens |