Title : Chronic cerebral hypoperfusion alters amyloid-β transport related proteins in the cortical blood vessels of Alzheimer's disease model mouse.

Pub. Date : 2019 Nov 15

PMID : 31415766






2 Functional Relationships(s)
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1 In contrast to wild type (WT) and APP23 mice, CCH strongly accelerated abnormal Abeta40 depositions and cerebral amyloid angiopathy (CAA) pathology, increased both LRP1 and RAGE expressions in brain parenchyma, while a decrease of LRP1 and an increase of RAGE were observed in vascular endothelial cells at age 12 months (M) of AD mice. 1-acetyl-2-(coumariniminecarboxamide-3-yl)hydrazine low density lipoprotein receptor-related protein 1 Mus musculus
2 In contrast to wild type (WT) and APP23 mice, CCH strongly accelerated abnormal Abeta40 depositions and cerebral amyloid angiopathy (CAA) pathology, increased both LRP1 and RAGE expressions in brain parenchyma, while a decrease of LRP1 and an increase of RAGE were observed in vascular endothelial cells at age 12 months (M) of AD mice. 1-acetyl-2-(coumariniminecarboxamide-3-yl)hydrazine low density lipoprotein receptor-related protein 1 Mus musculus