Title : Oxidative stress induced by palmitic acid modulates KCa2.3 channels in vascular endothelium.

Pub. Date : 2019 Oct 15

PMID : 31415760






1 Functional Relationships(s)
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1 KCa2.3-mediated vasodilatation responses to acetylcholine and NS309 (agonist of KCa2.3 and KCa3.1) were impaired by incubation of normal mesenteric arteries with 100 muM PA for 24 h. In cultured human umbilical vein endothelial cells (HUVECs), PA decreased KCa2.3 current and expression at mRNA and protein levels. 6,7-dichloro-1H-indole-2,3-dione 3-oxime potassium calcium-activated channel subfamily N member 4 Homo sapiens