Title : Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD+ Biosynthesis.

Pub. Date : 2019 Aug 1

PMID : 31415077






1 Functional Relationships(s)
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1 The replenishment of NMN or NAD+ partially slowed down corneal nerve fiber degeneration, reduced the epithelial defect in denervated mice, and improved apoptosis induction in FK866-treated cells by restoring the activation levels of SIRT1, AKT, and CREB. NAD sirtuin 1 Mus musculus