Title : Resveratrol prevents chronic intermittent hypoxia-induced cardiac hypertrophy by targeting the PI3K/AKT/mTOR pathway.

Pub. Date : 2019 Sep 15

PMID : 31412263






2 Functional Relationships(s)
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1 Further results indicated that PI3K/AKT pathway-mediated inhibition of the mammalian target of rapamycin (mTOR) pathway played a role in the activation of autophagy by resveratrol after CIH stimulation. Resveratrol AKT serine/threonine kinase 1 Homo sapiens
2 SIGNIFICANCE: In conclusion, resveratrol supplementation during CIH upregulates autophagy by targeting the PI3K/AKT/mTOR pathway, which appears to be beneficial for resisting cardiac hypertrophy. Resveratrol AKT serine/threonine kinase 1 Homo sapiens