Title : ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer.

Pub. Date : 2019 Aug 27

PMID : 31399545






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TP53 facilitated ARF6 activation by platelet-derived growth factor (PDGF), via its known function to promote the expression of PDGF receptor beta (PDGFRbeta) and enzymes of the mevalonate pathway (MVP). Mevalonic Acid tumor protein p53 Homo sapiens