Title : A metabolite of the carcinogen 7,12-dimethylbenz[a]anthracene that reacts predominantly with adenine residues in DNA.

Pub. Date : 1988 Sep

PMID : 3136949






2 Functional Relationships(s)
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1 Four 7,12-dimethylbenz[a]anthracene--deoxyribonucleoside adducts formed in mouse epidermis in vivo arise from the syn dihydrodiol epoxide metabolite of this carcinogen. dihydrodiol epoxide joined toes Mus musculus
2 With the synthetic syn dihydrodiol epoxide it was possible to identify three of these as deoxyadenosine adducts and to establish their structures. dihydrodiol epoxide joined toes Mus musculus