Title : Synchronous multiple primary gastrointestinal cancers with CDH1 mutations: A case report.

Pub. Date : 2019 Jul 6

PMID : 31367630






2 Functional Relationships(s)
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1 DNA sequencing performed on paraffin-embedded tissue revealed two exactly coincident alterations in CDH1, C.57T>G and C.1418A>T. CONCLUSION: This case suggests that the combination of CDH1 mutations and WNT/beta-catenin signaling activation contributes to the carcinogenesis of gastrointestinal SMPC. Paraffin cadherin 1 Homo sapiens
2 DNA sequencing performed on paraffin-embedded tissue revealed two exactly coincident alterations in CDH1, C.57T>G and C.1418A>T. CONCLUSION: This case suggests that the combination of CDH1 mutations and WNT/beta-catenin signaling activation contributes to the carcinogenesis of gastrointestinal SMPC. Paraffin cadherin 1 Homo sapiens