Title : Bradykinin-induced contraction is inhibited by tiaramide, an anti-inflammatory drug, with an inhibition of increase in intracellular free calcium.

Pub. Date : 1988 Aug

PMID : 3136243






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bradykinin stimulates phospholipase C, which leads to an increase in intracellular free Ca++, activation of phospholipase A2 and release of PGs in the PG-generating cells. Phosphatidylglycerols LOC100009319 Oryctolagus cuniculus
2 The released PGs act on smooth muscle cells to elicit contractions via phospholipase C activation and Ca++ mobilization. Phosphatidylglycerols LOC100009319 Oryctolagus cuniculus