Pub. Date : 2019
PMID : 31360208
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We also noticed that BP restored Ox-LDL-stimulated HUVECs oxidative stress, by induced antioxidant gene expressions, including Heme oxygenase-1 and its upstream mediator, Nrf2, which were mediated by the activation of the phosphorylation of PI3K/Akt/mTOR. | Benzo(a)pyrene | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Our results demonstrated that BP protected HUVECs against oxidative damage partly via PI3K/Akt/mTOR-mediated Nrf/HO-1 pathway, which might be applied into preventing Ox-LDL mediated cardiovascular diseases. | Benzo(a)pyrene | AKT serine/threonine kinase 1 | Homo sapiens |