Title : Physiologically Based Pharmacokinetic Modelling to Describe the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone According to Cytochrome P450 2D6 Phenotypes.

Pub. Date : 2020 Jan

PMID : 31359271






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Physiologically Based Pharmacokinetic Modelling to Describe the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone According to Cytochrome P450 2D6 Phenotypes. Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens
2 The goal of this study was to develop a physiologically based pharmacokinetic (PBPK) model considering the CYP2D6 genetic polymorphism for risperidone and 9-hydroxyrisperidone (9-OH-RIS) taking CYP3A4 into account. Paliperidone Palmitate cytochrome P450 family 2 subfamily D member 6 Homo sapiens