Title : Abrogation of FBW7α-dependent p53 degradation enhances p53's function as a tumor suppressor.

Pub. Date : 2019 Sep 6

PMID : 31346036






3 Functional Relationships(s)
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1 The polyubiquitylation of p53 occurred via Lys-48 linkage and involved phosphorylation on p53 at Ser-33 and Ser-37 by glycogen synthase kinase 3beta (GSK3beta) and DNA-dependent protein kinase (DNA-PK), respectively. Serine tumor protein p53 Homo sapiens
2 The polyubiquitylation of p53 occurred via Lys-48 linkage and involved phosphorylation on p53 at Ser-33 and Ser-37 by glycogen synthase kinase 3beta (GSK3beta) and DNA-dependent protein kinase (DNA-PK), respectively. Serine tumor protein p53 Homo sapiens
3 The polyubiquitylation of p53 occurred via Lys-48 linkage and involved phosphorylation on p53 at Ser-33 and Ser-37 by glycogen synthase kinase 3beta (GSK3beta) and DNA-dependent protein kinase (DNA-PK), respectively. Serine tumor protein p53 Homo sapiens