Title : Clinical and neurohumoral associates of variations in plasma Na+ in the PREVEND cohort.

Pub. Date : 2019 Oct 1

PMID : 31339776






3 Functional Relationships(s)
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1 Furthermore, plasma sodium levels were associated with log2 copeptin (males: st. beta=0.18, P<0.001; females: st. beta=0.17, P<0.001), log2 NT-proBNP (males: st. beta=0.07, P=0.008; females: st. beta=0.12, P<0.001) and log2 aldosterone (males: st. beta= -0.06, P=0.005; females: st. beta= -0.09, P<0.001). Sodium arginine vasopressin Homo sapiens
2 Copeptin and NT-proBNP showed interaction in their association with plasma sodium. Sodium arginine vasopressin Homo sapiens
3 Thus, our data support that [1] osmoregulation, as estimated from copeptin levels, is a main associate of plasma sodium, and moreover, [2] show a consistent association with volume markers, with higher NT-proBNP and lower aldosterone in subjects with higher plasma sodium. Sodium arginine vasopressin Homo sapiens