Title : Influence of AS3MT polymorphisms on arsenic metabolism and liver injury in APL patients treated with arsenic trioxide.

Pub. Date : 2019 Sep 15

PMID : 31330140






1 Functional Relationships(s)
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1 Our data promotes the realization that AS3MT 35587 (rs11191453), 35991 (rs10748835), especially their joint genotypes 35991 (rs10748835) AA / 35587 (rs11191453) TC+CC, is a novel predictive biomarker for the therapeutic efficacy of As2O3 in the treatment of APL. Arsenic Trioxide arsenite methyltransferase Homo sapiens