Pub. Date : 2019
PMID : 31327964
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Our results show that melatonin prevents LPS and Adenosine triphosphate (ATP) induced NLRP3 inflammasome activation in murine microglia in vitro, evidenced by inhibition of NLRP3 expression, Apoptosis-associated speck-like protein containing a CARD (ASC) speck formation, caspase-1 cleavage and interleukin-1beta (IL-1beta) maturation and secretion. | Adenosine Triphosphate | interleukin 1 beta | Mus musculus |