Title : Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity.

Pub. Date : 2019 Aug 23

PMID : 31321978






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Inactivation of CaN by forming the FKBP12-FK506-CaN ternary complex prevents the activation of nuclear factor of activated T cells (NF-AT), inhibiting the production of interleukin-2 and subsequent T-cell proliferation. Tacrolimus interleukin 2 Homo sapiens