Title : IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain.

Pub. Date : 2019 Jul 19

PMID : 31320508






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Inducible biosynthesis of prostaglandins, including the pro-algesic mediator prostaglandin E2 (PGE2), was decreased in myeloid cells that lack IRE1alpha or XBP1 but not other ER stress sensors. Dinoprostone X-box binding protein 1 Homo sapiens
2 Inducible biosynthesis of prostaglandins, including the pro-algesic mediator prostaglandin E2 (PGE2), was decreased in myeloid cells that lack IRE1alpha or XBP1 but not other ER stress sensors. Dinoprostone X-box binding protein 1 Homo sapiens
3 Functional XBP1 transactivated the human PTGS2 and PTGES genes to enable optimal PGE2 production. Dinoprostone X-box binding protein 1 Homo sapiens