Title : Molecular Mechanisms and Therapeutics for SCA17.

Pub. Date : 2019 Oct

PMID : 31317427






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Spinocerebellar ataxia type 17 (SCA17) is caused by polyglutamine (polyQ) expansion in the TATA box-binding protein (TBP), which functions as a general transcription factor. polyglutamine TATA-box binding protein Homo sapiens
2 Spinocerebellar ataxia type 17 (SCA17) is caused by polyglutamine (polyQ) expansion in the TATA box-binding protein (TBP), which functions as a general transcription factor. polyglutamine TATA-box binding protein Homo sapiens
3 Spinocerebellar ataxia type 17 (SCA17) is caused by polyglutamine (polyQ) expansion in the TATA box-binding protein (TBP), which functions as a general transcription factor. polyglutamine TATA-box binding protein Homo sapiens
4 Spinocerebellar ataxia type 17 (SCA17) is caused by polyglutamine (polyQ) expansion in the TATA box-binding protein (TBP), which functions as a general transcription factor. polyglutamine TATA-box binding protein Homo sapiens
5 The well-characterized function of TBP and typical neurodegeneration in SCA17 give us opportunities to understand how polyQ expansion causes selective neurodegeneration and to develop effective therapeutics. polyglutamine TATA-box binding protein Homo sapiens