Pub. Date : 2019 Sep 4
PMID : 31303442
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | One example is the targeted delivery of ASOs to hepatocytes, achieved with N-acetylgalactosamine (GalNAc) conjugation to ASO, which results in selective uptake by asialoglycoprotein receptor (ASGR). | N-acetylgalactosaminuronic acid | asialoglycoprotein receptor 1 | Mus musculus |
| 2 | The activity of GalNAc-conjugated ASOs was superior to that of the unconjugated parental ASO in ASGR (+) human HCC cells in vitro, but not in ASGR (-) cells. | N-acetylgalactosaminuronic acid | asialoglycoprotein receptor 1 | Mus musculus |