Title : Adenovirus oncoprotein E4orf6 triggers Cullin5 neddylation to activate the CLR5 E3 ligase for p53 degradation.

Pub. Date : 2019 Sep 3

PMID : 31301771






1 Functional Relationships(s)
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1 The Nedd8-activating enzyme inhibitor MLN4924 decreased E4orf6-induced neddylation of the cullin5 protein and subsequently suppressed p53 degradation. pevonedistat tumor protein p53 Homo sapiens