Title : Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters.

Pub. Date : 2019 Jul 11

PMID : 31294688






1 Functional Relationships(s)
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1 During the activating phase of the circadian cycle, the lysine acetyltransferase TIP60 acetylates the transcriptional activator BMAL1 leading to recruitment of BRD4 and the pause release factor P-TEFb, followed by productive elongation of circadian transcripts. Lysine aryl hydrocarbon receptor nuclear translocator-like Mus musculus