Title : Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors.

Pub. Date : 2019 Jul 9

PMID : 31288832






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Double/triple-hit lymphomas (DHL/THL) account for 5-10% of diffuse large B cell lymphoma (DLBCL) with rearrangement of MYC and BCL2 and/or BCL6 resulting in MYC overexpression. Orlistat MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 Double/triple-hit lymphomas (DHL/THL) account for 5-10% of diffuse large B cell lymphoma (DLBCL) with rearrangement of MYC and BCL2 and/or BCL6 resulting in MYC overexpression. Orlistat MYC proto-oncogene, bHLH transcription factor Homo sapiens