Pub. Date : 2019
PMID : 31285857
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation. | celastrol | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | As expected, celastrol pretreatment strikingly inhibited NLRP3 inflammasome activation and MC proliferation triggered by ox-LDL. | celastrol | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | In summary, celastrol potently blocked ox-LDL-induced MC proliferation, possibly by inhibiting NLRP3 inflammasome activation. | celastrol | NLR family pyrin domain containing 3 | Homo sapiens |