Title : Trehalose-induced slowdown of lysozyme hydration dynamics probed by EDLS spectroscopy.

Pub. Date : 2019 Jul 7

PMID : 31272172






3 Functional Relationships(s)
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1 We use extended depolarized light scattering spectroscopy to study the dynamics of water in a lysozyme-trehalose aqueous solution over a broad time scale, from hundreds to fractions of picoseconds. Water lysozyme Homo sapiens
2 By comparing aqueous solutions of lysozyme with and without trehalose, we show that the combined action of sugar and protein produces an exceptional dynamic slowdown of a fraction of water molecules around the protein, which become more than twice slower than in the absence of trehalose. Water lysozyme Homo sapiens
3 On the basis of these findings, we believe such ultraslow water close to the lysozyme is likely to be involved in the mechanism of bioprotection. Water lysozyme Homo sapiens