Title : Identification of Mutations in the mrdA Gene Encoding PBP2 That Reduce Carbapenem and Diazabicyclooctane Susceptibility of Escherichia coli Clinical Isolates with Mutations in ftsI (PBP3) and Which Carry bla NDM-1.

Pub. Date : 2019 Jul 3

PMID : 31270174






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We identified mutations in the mrdA gene encoding the PBP2 protein in two Escherichia coli bla NDM-1 clinical isolates that reduce susceptibility to carbapenems and to the intrinsic antibacterial activity of a diazabicyclooctane (DBO) PBP2 and beta-lactamase inhibitor. Carbapenems beta-lactamase Escherichia coli