Title : The AURORA of a New Way to Value Myeloid Immunosuppression in Cancer.

Pub. Date : 2019 Jul 1

PMID : 31262832






1 Functional Relationships(s)
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1 In this issue of Cancer Research, Yin and colleagues demonstrate unequivocally that the Aurora A kinase inhibitor, alisertib, specifically neutralizes MDSCs and triggers the rapid accrual of cytotoxic T cells, with consequent tumor clearance potentiated by PD-L1 blockade. MLN 8237 CD274 molecule Homo sapiens