Title : The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells.

Pub. Date : 2019 Jul 1

PMID : 31262352






1 Functional Relationships(s)
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1 Since glutathione is a central component of a complex system involved in preserving cellular redox status, we aimed to study whether the expression of the glutathione reductase (Gsr) gene, which encodes an essential enzyme for cellular redox homeostasis, is modulated by the transcription factors critical for self-renewal and pluripotency of ESCs. Glutathione gutter shaped root Mus musculus