Pub. Date : 2019 Jun 1
PMID : 31244286
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Metformin Modulates Cyclin D1 and P53 Expression to Inhibit Cell Proliferation and to Induce Apoptosis in Cervical Cancer Cell Lines. | Metformin | tumor protein p53 | Homo sapiens |
2 | Moreover, 30 mM or higher doses of metformin increase significantly p53 expression (p< 0.001). | Metformin | tumor protein p53 | Homo sapiens |
3 | Conclusion: Metformin can modulate cyclin D1 and p53 expression in HeLa cancer cell line, leadingto inhibition of cell proliferation and induction of apoptosis. | Metformin | tumor protein p53 | Homo sapiens |