Title : Metformin Modulates Cyclin D1 and P53 Expression to Inhibit Cell Proliferation and to Induce Apoptosis in Cervical Cancer Cell Lines.

Pub. Date : 2019 Jun 1

PMID : 31244286






3 Functional Relationships(s)
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1 Metformin Modulates Cyclin D1 and P53 Expression to Inhibit Cell Proliferation and to Induce Apoptosis in Cervical Cancer Cell Lines. Metformin tumor protein p53 Homo sapiens
2 Moreover, 30 mM or higher doses of metformin increase significantly p53 expression (p< 0.001). Metformin tumor protein p53 Homo sapiens
3 Conclusion: Metformin can modulate cyclin D1 and p53 expression in HeLa cancer cell line, leadingto inhibition of cell proliferation and induction of apoptosis. Metformin tumor protein p53 Homo sapiens