Title : miR-144 regulates oxidative stress tolerance of thalassemic erythroid cell via targeting NRF2.

Pub. Date : 2019 Sep

PMID : 31243572






2 Functional Relationships(s)
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1 In alpha-thalassemia, miR-144 and NRF2 target are associated with glutathione level and anemia severity. Glutathione microRNA 144 Homo sapiens
2 This study reveals that miR-144 expression was upregulated, whereas NRF2 expression and glutathione levels were decreased in comparison with the untreated condition after miR mimic transfection, while the reduction of miR-144 expression contributed to the increased NRF2 expression and glutathione level compared with the untreated condition after miR inhibitor transfection. Glutathione microRNA 144 Homo sapiens