Title : Apical sodium-dependent bile acid transporter inhibition with volixibat improves metabolic aspects and components of non-alcoholic steatohepatitis in Ldlr-/-.Leiden mice.

Pub. Date : 2019

PMID : 31233523






1 Functional Relationships(s)
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1 Gene profiling showed that volixibat reversed the inhibitory effect of the HFD on metabolic master regulators, including peroxisome proliferator-activated receptor-gamma coactivator-1beta, insulin receptor, and sterol regulatory element-binding transcription factor 2. volixibat insulin receptor Mus musculus