Pub. Date : 2020 Jul
PMID : 31215752
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cannabidiol inhibits sucrose self-administration by CB1 and CB2 receptor mechanisms in rodents. | Cannabidiol | cannabinoid receptor 2 (macrophage) | Mus musculus |
| 2 | Similarly, pretreatment with AM251, a CB1R antagonist, potentiated, while AM630, a selective CB2R antagonist, blocked CBD-induced reduction in sucrose self-administration, suggesting the involvement of CB1 and CB2 receptors. | Cannabidiol | cannabinoid receptor 2 (macrophage) | Mus musculus |
| 3 | Similarly, pretreatment with AM251, a CB1R antagonist, potentiated, while AM630, a selective CB2R antagonist, blocked CBD-induced reduction in sucrose self-administration, suggesting the involvement of CB1 and CB2 receptors. | Cannabidiol | cannabinoid receptor 2 (macrophage) | Mus musculus |
| 4 | Pretreatment with AM251 enhanced, while AM630 blocked JWH133-induced reduction in sucrose self-administration in WT mice, suggesting that CBD inhibits sucrose self-administration likely by CB1 receptor antagonism and CB2 receptor agonism. | Cannabidiol | cannabinoid receptor 2 (macrophage) | Mus musculus |