Title : Studies on the pregnenolone-16 alpha-carbonitrile-inducible form of rat liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase.

Pub. Date : 1987 Nov 15

PMID : 3120728






1 Functional Relationships(s)
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1 Treatment of rats with pregnenolone-16 alpha-carbonitrile (PCN) markedly induces rat liver microsomal cytochrome P-450p and UDP-GT-dt1, a glucuronosyltransferase active towards the digitoxin metabolite, digitoxigenin monodigitoxoside. Digitoxin cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus