Pub. Date : 2019 Dec
PMID : 31206670
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ADP-ribosylation factor 6 (Arf6) is a small GTPase with pleiotropic effects and has previously been shown to regulate ATP-binding cassette transporter 1 (ABCA1) recycling, and thus, cholesterol homeostasis. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
| 2 | Our results demonstrate that HG-induced cholesterol accumulation and cellular injury in podocytes may be related to the recycling disorder of ABCA1 caused by the downexpression of Arf6 in DKD. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |