Title : Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells.

Pub. Date : 2019 Jul

PMID : 31203411






1 Functional Relationships(s)
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1 However, cell pretreatment with 8-methoxypsoralen (0.1-1 microM), a potent inhibitor of CYP2A, resulted in a 90% decrease of 4-ABP DNA adducts levels. Methoxsalen cytochrome P450 family 2 subfamily A member 13 Homo sapiens