Title : Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis.

Pub. Date : 2019 Oct

PMID : 31201114






1 Functional Relationships(s)
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1 Our results indicate that loss of Nf1 stimulates PKCdelta-mediated p47phox phosphorylation via RAS activation, leading to increased NADPH oxidase 2 activity, reactive oxygen species generation, membrane ruffling and macropinocytosis. Oxygen neurofibromin 1 Mus musculus