Title : Dynamic ensemble of HIV-1 RRE stem IIB reveals non-native conformations that disrupt the Rev-binding site.

Pub. Date : 2019 Jul 26

PMID : 31199872






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 The ESs disrupt the Rev-binding site by changing local secondary structure, and their stabilization via point substitution mutations decreases the binding affinity to the Rev arginine-rich motif (ARM) by 15- to 80-fold. Arginine Rev Human immunodeficiency virus 1
2 The ESs disrupt the Rev-binding site by changing local secondary structure, and their stabilization via point substitution mutations decreases the binding affinity to the Rev arginine-rich motif (ARM) by 15- to 80-fold. Arginine Rev Human immunodeficiency virus 1