Title : New insights into the transcriptional regulation of aquaporin-2 and the treatment of X-linked hereditary nephrogenic diabetes insipidus.

Pub. Date : 2019 Jun 30

PMID : 31189221






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Water reabsorption in the CD depends on the action of arginine vasopressin (AVP) and a transepithelial osmotic gradient between the luminal fluid and surrounding interstitium. Water arginine vasopressin Homo sapiens
2 AVP induces transcellular water reabsorption across CD principal cells through associated signaling pathways after binding to arginine vasopressin receptor 2 (AVPR2). Water arginine vasopressin Homo sapiens
3 Specifically, AVP stimulates the intracellular translocation of AQP2-containing vesicles to the apical plasma membrane, increasing the osmotic water permeability of CD cells. Water arginine vasopressin Homo sapiens