Title : Mechanistic Basis of Cabotegravir-Glucuronide Disposition in Humans.

Pub. Date : 2019 Aug

PMID : 31175220






1 Functional Relationships(s)
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1 Cabotegravir, a novel integrase inhibitor under development for treatment and prevention of HIV, is primarily metabolized by UDP-glucuronosyltransferase (UGT)1A1 and UGT1A9 to a direct ether glucuronide metabolite. ether glucuronide UDP glucuronosyltransferase family 1 member A9 Homo sapiens