Pub. Date : 2019 Jun
PMID : 31174699
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, results showed that pretreatment with rapamycin reduced the pyroptosis of peritoneal macrophages stimulated by cecal contents and the release of inflammatory factors such as interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha); In septic mice, rapamycin treatment decreased the activation of inflammasome in lung, and alleviated the pathological injuries in lung, liver and spleen tissues during acute stage of sepsis. | Sirolimus | interleukin 1 beta | Mus musculus |
| 2 | Here, results showed that pretreatment with rapamycin reduced the pyroptosis of peritoneal macrophages stimulated by cecal contents and the release of inflammatory factors such as interleukin-1beta (IL-1beta), tumor necrosis factor-alpha (TNF-alpha); In septic mice, rapamycin treatment decreased the activation of inflammasome in lung, and alleviated the pathological injuries in lung, liver and spleen tissues during acute stage of sepsis. | Sirolimus | interleukin 1 beta | Mus musculus |