Title : Synthesis and Preliminary Biological Evaluation of Two Fluoroolefin Analogs of Largazole Inspired by the Structural Similarity of the Side Chain Unit in Psammaplin A.

Pub. Date : 2019 Jun 3

PMID : 31163697






1 Functional Relationships(s)
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1 Largazole, isolated from a marine Cyanobacterium of the genus Symploca, is a potent and selective Class I HDAC (histone deacetylation enzymes) inhibitor. largazole histone deacetylase 9 Homo sapiens