Pub. Date : 2019
PMID : 31160894
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARgamma/SGK1 signaling pathway. | Rosiglitazone | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |
| 2 | The peroxisome proliferator-activated receptor gamma (PPARgamma) agonist rosiglitazone was shown to stimulate ENaC-mediated salt absorption in the kidney. | Rosiglitazone | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |
| 3 | Conclusions: Rosiglitazone ameliorated the lung injury and promoted ENaC-mediated AFC via a PPARgamma/SGK1-dependent signaling pathway, alleviating pulmonary edema in a mouse model of ALI. | Rosiglitazone | sodium channel, nonvoltage-gated 1 alpha | Mus musculus |