Title : Near-Infrared Aggregation-Induced Emission-Active Probe Enables in situ and Long-Term Tracking of Endogenous β-Galactosidase Activity.

Pub. Date : 2019

PMID : 31139612






2 Functional Relationships(s)
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1 In this work, we developed an elaborated near-infrared (NIR) aggregation-induced emission (AIE)-active fluorescent probe, which is composed of a hydrophobic 2-(2-hydroxyphenyl) benzothiazole (HBT) moiety for extending into the NIR wavelength, and a hydrophilic beta-galactosidase (beta-gal) triggered unit for improving miscibility and guaranteeing its non-emission in aqueous media. hbt galactosidase beta 1 Homo sapiens
2 In this work, we developed an elaborated near-infrared (NIR) aggregation-induced emission (AIE)-active fluorescent probe, which is composed of a hydrophobic 2-(2-hydroxyphenyl) benzothiazole (HBT) moiety for extending into the NIR wavelength, and a hydrophilic beta-galactosidase (beta-gal) triggered unit for improving miscibility and guaranteeing its non-emission in aqueous media. hbt galactosidase beta 1 Homo sapiens