Title : VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.

Pub. Date : 2020 Jan 15

PMID : 31125123






2 Functional Relationships(s)
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1 VPS33B overexpression suppressed CRC proliferation, intrahepatic metastasis and chemoresistance of cisplatin (DDP) in vivo and in vitro through modulating the epidermal growth factor receptor (EGFR)/RAS/ERK/c-Myc/p53/miR-133a-3p feedback loop and the downstream cell cycle or EMT-related factors. Cisplatin VPS33B late endosome and lysosome associated Homo sapiens
2 VPS33B overexpression suppressed CRC proliferation, intrahepatic metastasis and chemoresistance of cisplatin (DDP) in vivo and in vitro through modulating the epidermal growth factor receptor (EGFR)/RAS/ERK/c-Myc/p53/miR-133a-3p feedback loop and the downstream cell cycle or EMT-related factors. Cisplatin VPS33B late endosome and lysosome associated Homo sapiens