Pub. Date : 2020
PMID : 31123029
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | JAK inhibitors or a selective STAT5 SH2 domain inhibitor induced cell death and Ruxolitinib blocked T-cell neoplasia in vivo We conclude that enhanced STAT5A or STAT5B action both drive peripheral T-cell lymphoma development, defining both STAT5 molecules as targets for therapeutic intervention. | ruxolitinib | signal transducer and activator of transcription 5A | Mus musculus |
| 2 | JAK inhibitors or a selective STAT5 SH2 domain inhibitor induced cell death and Ruxolitinib blocked T-cell neoplasia in vivo We conclude that enhanced STAT5A or STAT5B action both drive peripheral T-cell lymphoma development, defining both STAT5 molecules as targets for therapeutic intervention. | ruxolitinib | signal transducer and activator of transcription 5A | Mus musculus |
| 3 | JAK inhibitors or a selective STAT5 SH2 domain inhibitor induced cell death and Ruxolitinib blocked T-cell neoplasia in vivo We conclude that enhanced STAT5A or STAT5B action both drive peripheral T-cell lymphoma development, defining both STAT5 molecules as targets for therapeutic intervention. | ruxolitinib | signal transducer and activator of transcription 5A | Mus musculus |