Pub. Date : 2019 Jun 25
PMID : 31117376
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that intravenous administration of exosomes produced by MSCs stimulated by IFNgamma (IFNgamma-Exo) (i) reduced the mean clinical score of EAE mice compared to PBS control, (ii) reduced demyelination, (iii) decreased neuroinflammation, and (iv) upregulated the number of CD4+CD25+FOXP3+ regulatory T cells (Tregs) within the spinal cords of EAE mice. | Lead | interferon gamma | Mus musculus |
| 2 | We found that intravenous administration of exosomes produced by MSCs stimulated by IFNgamma (IFNgamma-Exo) (i) reduced the mean clinical score of EAE mice compared to PBS control, (ii) reduced demyelination, (iii) decreased neuroinflammation, and (iv) upregulated the number of CD4+CD25+FOXP3+ regulatory T cells (Tregs) within the spinal cords of EAE mice. | Lead | interferon gamma | Mus musculus |